Face - PRP & Stem Cell Rejuvenation in London, UK
“Experience London’s Most Advanced Regenerative Facial Rejuvenation”
“Using gold-standard PRP and autologous ExoSmart therapy, we unlock your skin’s true regenerative power.”
Rejuvence Clinic offers the most advanced regenerative treatments in the UK for natural facial rejuvenation. Using your own biology—platelets, plasma, exosomes and fat-derived tissue—we restore skin quality, stimulate collagen and reverse signs of ageing without synthetic fillers. Our options range from high-grade PRP to next-generation Exosmart™ autologous exosomes, providing safe, powerful skin regeneration with minimal downtime and natural-looking results.
As the first UK clinic to offer Exosmart™, we lead in autologous exosome therapy, delivering impressive improvements in texture, firmness and radiance. For patients needing deeper rejuvenation or volume, we also provide fat grafting and nanofat, enhancing structure and long-term collagen support. Whether used alone or combined, our treatments—PRP, Exosmart™, nanofat and micro-fat transfer—offer a complete regenerative toolkit for firmer, brighter and more youthful skin.
Your Specialist in Regenerative Aesthetics
All PRP, Exosmart™, nanofat and regenerative treatments at Rejuvence Clinic are led by Dr Sam Ghani, a recognised UK leader in regenerative medicine. He has long overseen regenerative services and remains actively engaged in international workshops, conferences and specialist training to stay at the forefront of emerging techniques.
Dr Ghani combines his passion for innovation with a clear understanding of what is safe, ethical and legally practicable in the UK, ensuring patients receive advanced yet compliant care. He is also involved in ongoing research collaborations and works closely with biomedical companies to help introduce next-generation regenerative technologies—such as secretome therapies—into the UK market.
What is PRP and how does it help the skin?
Platelet Rich Plasma – commonly referred to as PRP – is a natural cell based treatment for facial rejuvenation and can help slow down the ageing process.
Platelets are specific cells found in the blood that are responsible for clotting and initiating inflammation and repair processes within the body. Platelet Rich Plasma (PRP) is a process whereby the platelets are removed from your blood and purified into a liquid form – ‘plasma’ – with a concentration at least 4-5 times higher than in blood.
Platelets have been shown to play an important role in wound healing. When activated they trigger the release and production of multiple chemicals that ultimately result in the stimulation of fibroblasts. Fibroblasts are cells that produce collagen and elastin. Collagen and elastin form the main building blocks of the skin. Increased collagen and elastin results in improved skin health. Platelet rich plasma reinvigorates the skin and this can have dramatic effects, especially when you consider skin becomes inactive by the age of 30.
How is PRP performed?
Rejuvence Clinic is a centre of excellence for Platelet Rich Plasma. We offer a three tiered PRP service. Our Level I service is our entry level PRP – Neogenesis PRP. We are authorised providers for Magellan TruPRP™ (Level II) and Angel Arthrex™ PRP (Level III) systems.
Our Advanced Platelet Rich Plasma (PRP) Treatments for hair loss are non-invasive procedures.PRP is a completely natural treatment and produced using your own blood. Blood is taken and subsequently run through a machine known as a centrifuge. The centrifuge separates the blood into its different cellular components. Once finished, centrifugation will split your blood samples into different layers of cells and the platelet rich plasma layer is extracted using a syringe manually. Our Level I Neogenesis System uses a swing out centrifuge set-up and produces PRP in this manner.
The Angel Arthrex™ and Magellan TruPRP™ systems are based around very advanced centrifuges that are completely automated and able to identify the platelets in your blood, concentrate and extract them. Both Angel and Magellan are able to produce very high concentrations of PRP needed for effective treatment of hair loss especially male and female pattern hair loss.
Once the PRP is ready this is injected into the affected areas of the face using an automated injector device. At Rejuvence Clinic we recommend a series of 3 treatments over 3 months for all patients new to PRP. Our PRP treatments can also be combined with Hyaluronic Acid Mesotherapy (Filorga NCTF 135HA) as well as other treatments we provide including Hydrafacial.
Not all PRP is the same. How is Rejuvence different to other clinics?
PRP is widely available in clinics across the UK. However, there is a large variation in the cost of treatments. It is important to understand that not all PRP is the same. For PRP to be effective it is generally agreed that the concentration of platelets needs to be at least 4 to 5 times higher than in blood. The majority of PRP systems used in clinics across the UK claim to achieve this concentration but that is simply not true. At best test tube centrifugation systems used by the majority of clinics can achieve only 2 times concentration.
Three Tiered PRP Treatments for everyone!
We consider ourselves a centre of excellence for PRP. Hence we have taken great care and effort to ensure we use only the best systems in our clinic to ensure we deliver high quality PRP to all our clients.
We have a three tiered PRP service at Rejuvence Clinic.
Level I
Our entry level PRP system is the Neogenesis PRP system. This is a more conventional PRP system and involves collecting 30ml of blood to produce 2-4ml of PRP with a concentration in the range of 2-3 times. This is effective for those on a budget. It uses a swing out centrifuge and a single spin cycle. Our Level I PRP treatment is still better than most thanks to a superior centrifuge and larger volume syringes. However, we do recommend Magellan TruPRP and Angel Arthrex for those looking for the best outcome. Neogenesis PRP does not require a consultation prior to booking.
All PRP treatments can also be combined with Filorga Hyaluronic Acid Mesotherapy and Hydrafacial for even better results.
Level II
The Magellan TruPRP system is a very high end PRP system. It involves blood draw of between 60 and 120ml of blood. It yields 6-12 ml of high concentration PRP with platelets counts in the region of 4-5 times higher than baseline. The Magellan TruPRP system use a specialised centrifuge that runs a 2 spin protocol incorporating a hard and a soft spin. The machine is fully automated with density scanning. All Level II PRP treatments for facial rejuvenation require a consultation with one of our doctors beforehand.
Level II Magellan PRP treatments can also be combined with Filorga Hyaluronic Acid Mesotherapy and Hydrafacial for even better results. Book your consultation now.
Level III
The Angel Arthrex System is our gold standard PRP unit. This Involves a blood draw of between 60 and 180ML. It can yield between 6 to 18ml of high concentration PRP with platelet counts in the region of 4-5 times higher than baseline. The Angel Arthrex system uses a specialised centrifuge that runs a two spin program similar to Magellan TruPRP. The Angel system also incorporates a density scanning function ensuring consistent and automated PRP production. The difference between Angel Arthrex and Magellan TruPRP is that the Angel system allows for customisation of the specific cellular constituents of the PRP as well as larger volume of PRP. If you are looking for the best PRP for facial rejuvenation we always recommend Angel Arthrex. All Level III PRP treatments for facial rejuvenation require a consultation with one of our doctors beforehand.
As part of a package we can also offer PRP with Filorga Hyaluronic Acid Mesotherapy and/or Hydrafacial. The possibilities are truly endless.
How long is the recovery?
We normally advise clients to take a couple of days off work. There can be some mild bruising and swelling associated with the injections to the various regions in the face. We advise against using ice and heat packs to help with the swelling as this can compromise PRP effects. Over the counter pain medication such as paracetamol is normally sufficient. Arnica is also recommended to help with any bruising. Smoking is absolutely contraindicated as it can prolong the healing time and more importantly it can seriously compromise PRP.
Exosmart™ Autologous Exosomes – Advanced Natural Facial Rejuvenation
Rejuvence Clinic is proud to be the first clinic in the UK to offer Exosmart™, a breakthrough autologous exosome system that elevates PRP skin rejuvenation to a new level. Using only your own biological material, Exosmart™ delivers smoother, brighter, firmer and more youthful skin—naturally and safely, without synthetic additives or donor tissue.
What Are Autologous Exosomes?
Exosomes are tiny regenerative messengers released by platelets that carry growth factors, proteins, peptides and microRNAs to stimulate repair. When concentrated from your own PRP, they boost collagen and elastin, enhance hydration, smooth fine lines and significantly improve tone and texture. Because they are fully autologous, there is no risk of allergy or rejection, making Exosmart™ one of the safest and most natural methods of skin rejuvenation.
How Exosmart™ Works
Exosmart™ is a CE-MDR certified medical device that converts PRP into a high-potency exosome-rich serum using patented 15 kDa ultrafiltration.
Treatment steps:
- Simple blood draw
- PRP processing
- Ultrafiltration through the Exosmart™ membrane
- Production of a 6 mL autologous exosome serum
- Injection or microneedling into the skin
The procedure takes around 30 minutes with minimal downtime. A healthy glow appears in days, with deeper improvements continuing over several weeks as collagen renews.
Expected Results
Exosmart™ can deliver:
- Brighter, more even skin tone
- Firmer, more elastic skin
- Reduced lines and under-eye hollowing
- Smoother texture and reduced scarring
- Enhanced hydration and glow
Results appear within weeks and continue to improve for months. It can be used on the face, under-eyes, neck and décolletage, and pairs excellently with laser or microneedling to boost recovery.
Exosmart™ vs PRP
Both PRP and Exosmart™ rejuvenate the skin, but Exosmart™ offers 10–50× more regenerative signalling and delivers faster, deeper and longer-lasting results. Many patients notice improvements after 1–2 treatments instead of multiple PRP sessions. It is highly effective for fine lines, under-eye hollowness, acne scars, crepey skin, dullness and sun damage.
Exosmart™ vs Off-the-Shelf Exosomes
Many clinics use pre-packaged exosome brands such as ExoCel Bio, AnteAGE®, BENEV, or Exo|E, which are derived from donor placenta, cord blood or cell cultures. These products can vary in potency, may degrade in storage, and sit in a regulatory grey zone.
Exosmart™ is different:
- 100% autologous (from your own blood)
- No donor tissue, preservatives or foreign proteins
- Produced fresh at the moment of treatment
- Higher purity and consistency
- Fully compliant as a CE-MDR certified device
This makes Exosmart™ safer, more potent and more predictable than off-the-shelf alternatives.
Why Choose Rejuvence Clinic?
As the first UK clinic to offer Exosmart™, Rejuvence provides unrivalled expertise in PRP, microneedling and regenerative medicine. Treatments are fully personalised, biologically matched to you, and designed to achieve natural, long-lasting improvements that exceed the results of PRP or off-the-shelf exosome treatments.
For those seeking the most advanced natural facial rejuvenation in London, Exosmart™ at Rejuvence Clinic offers a new gold standard. Ready to discover the power of your own exosomes? Book a consultation and experience next-generation facial rejuvenation at Rejuvence Clinic.
Combining PRP & Exosmart™ with Advanced Skin-Technologies for Maximum Effect
Aerolase Neo Elite & Era Elite (“Reverse Neo” Protocol)
At Rejuvence Clinic we use the Aerolase Neo Elite (1064 nm Nd:YAG, 650 µs pulse) and the Era Elite (Er:YAG, 300 µs pulse) in a combined “Reverse Neo” protocol. The Neo stimulates deep dermal collagen, while the Era resurfaces the upper skin layers — together they achieve full-thickness skin renewal. When you combine this with PRP or Exosmart™ exosome treatment, you are layering regenerative signal (from your platelets/exosomes) on top of laser-induced tissue remodelling. This synergy accelerates healing, enhances texture, and upgrades tone for a truly advanced rejuvenation outcome.
BBL HEROic by Sciton® (BroadBand Light Therapy)
The Sciton BBL HEROic broadband‐light system treats sun damage, pigmentation, redness, vascular lesions and age-related skin changes. Oblique+1 When paired with PRP or Exosmart™, you get photorejuvenation (via BBL) plus regenerative therapy (via PRP/exosomes) — meaning clearer, brighter skin tone plus structural improvement underneath. At Rejuvence this layered approach allows us to treat both visible surface issues and stimulate cellular regeneration simultaneously.
Sylfirm X Radio Frequency Microneedling
The Sylfirm X combines microneedling with radio-frequency energy, including dual-wave modes to address fine lines, laxity, pigmentation and vascular issues. RealSelf.com Clinical reports show that combining RF microneedling with exosome therapy yields superior results in collagen deposition, skin tightening and texture improvement. When we integrate PRP or Exosmart™ post-Sylfirm, we amplify those healing signals, giving more rapid improvement with less downtime.
How These Combinations Work Together
- First, we may use a laser or RF microneedling device to create controlled tissue injury and stimulate the healing cascade (for example, Neo Elite, Era Elite, BBL or Sylfirm X).
- Immediately following (or shortly after), we administer PRP or Exosmart™ (autologous exosomes) to accelerate regeneration, boost collagen/elastin production and enhance skin repair.
- This layered strategy allows us to customise the treatment plan to your skin condition, goals and downtime preferences — whether you want texture refinement, tightening, pigmentation correction or full rejuvenation.
- The result: faster visible improvements, deeper biological change, longer-lasting outcomes and a more natural look, because we are using your own regenerative biology rather than just surface treatment.
Fat Grafting & Stem-Cell Rejuvenation at Rejuvence Clinic
At Rejuvence Clinic, we offer fat grafting and stem-cell–rich nanofat rejuvenation as part of our advanced regenerative treatments for natural facial enhancement. This approach uses your body’s own fat and stem-cell–dense tissue to restore youthful contours, improve skin quality and deliver long-lasting rejuvenation that synthetic fillers simply cannot achieve.
What Is Stem-Cell Rejuvenation?
Stem-cell rejuvenation involves the careful injection of your own fat into targeted facial areas to replace lost volume and reinvigorate ageing tissues. Using minimally invasive liposuction techniques, fat is gently harvested and processed into two forms:
1. Structural Fat Grafting (for Volume)
Once purified, the fat is injected back into the face much like a natural filler. These injections are placed within the facial muscles and deeper layers to replace the fat that diminishes with age—restoring fullness to areas such as the cheeks, temples, mid-face, jawline and under-eyes. Because this fat contains living cells and regenerative properties, the results are soft, natural and long-lasting.
2. Nanofat / Micronised Fat (for Skin Quality)
A portion of the harvested fat is micronised (filtered) into a fine liquid rich in stem cells and growth factors. This nanofat is injected just beneath the skin, where it enhances regeneration, stimulates collagen and elastin, improves crepey skin and helps reduce pigmentation—particularly under the eyes. The effect is healthier, brighter, smoother skin with significantly improved texture and tone.
Who is a candidate for Stem Cell Rejuvenation?
Candidates for stem cell rejuvenation are males and females of varying ages suffering with regions of volume loss, under eye dark circles, fine lines and wrinkles as well as a generalised sallow complexion and loss of glow to the skin.
A Natural, Long-Lasting Return to Youth
By combining volume restoration with stem-cell–driven skin renewal, fat grafting delivers a unique and impressive rejuvenation. Results can last many years, provided a healthy lifestyle is maintained, because the transplanted fat integrates and survives as living tissue.
Combining Fat Grafting with PRP & Exosmart™
For even greater regenerative impact, fat grafting and nanofat can be paired with PRP or Exosmart™ autologous exosomes. These biologically active treatments enhance fat survival, boost stem-cell activation, accelerate healing and intensify improvements in skin firmness, elasticity and radiance. When used together, they create one of the most advanced and natural approaches to full-face rejuvenation available in the UK.
