Male Pattern Hair Loss Treatments, London
"Where medical expertise meets regenerative science—doctor-led solutions designed to rebuild density, strengthen follicles and restore confidence."
When Rejuvence Clinic was founded by Dr Ghani and Dr Amin, hair restoration and the use of cutting-edge regenerative medicine were central to our mission. From the beginning, we aimed to offer clients the most advanced techniques using the highest-quality systems, while integrating these with proven medical treatments to directly target the underlying science of hair loss. Over the years, this commitment has allowed us to achieve excellent, consistent results and support countless men in managing and improving male pattern hair loss.
What Is Male Pattern Hair Loss?
Male pattern hair loss (androgenetic alopecia) is the most common cause of hair thinning in men, affecting millions across the UK. It is a hereditary condition driven by a combination of genetics, hormone sensitivity and gradual changes in the hair cycle. Normally, the hair cycle moves through three stages: anagen (active growth), catagen (transition) and telogen (resting and shedding).
In androgenetic alopecia, the hormone dihydrotestosterone (DHT) shortens the anagen phase and progressively weakens the hair follicle. This leads to miniaturisation—a process where follicles shrink and produce finer, shorter, lighter hairs until growth becomes barely visible. At Rejuvence Clinic, we identify miniaturisation through dermatoscopy, which reveals classic signs such as thinning hair shafts, variation in follicle diameter and an increased number of single-hair units. This detailed assessment helps us diagnose hair loss accurately and create the most effective treatment plan for each patient.
Can DHT Levels Be Measured—and Does It Matter?
Although DHT can be measured with a blood test, the results are not very meaningful in diagnosing or managing male pattern hair loss. This is because androgenetic alopecia depends more on follicular sensitivity to DHT, not the overall hormone level circulating in the bloodstream. Men with normal—or even low—DHT levels can still develop significant hair loss if their follicles are genetically susceptible.
For this reason, DHT testing rarely changes treatment decisions, and specialist hair clinics like Rejuvence Clinic rely instead on the scalp examination, dermatoscopic findings and clinical pattern to guide the most appropriate medical and regenerative treatment options.
How is Male Pattern Hair Loss graded?
The Hamilton – Norwood classification is the gold standard classification system for male pattern hair loss due to androgenic alopecia. Characteristically there is shrinking of hairs with hair loss generally starting at the front of the hair line extending towards the top of the scalp and backwards.
Comprehensive Treatment for Male Pattern Hair Loss at Rejuvence Clinic
Understanding Male Pattern Hair Loss
Male pattern hair loss is the most common cause of thinning in men across the UK and often requires a multi-layered, long-term treatment approach. At Rejuvence Clinic, we provide a comprehensive range of medical, dermatological and regenerative hair-loss treatments tailored to every stage of androgenetic alopecia.
Medical Treatments to Support Hair Strength and Growth
Core options may include topical hair-regrowth solutions, oral medications, caffeine-based shampoos, DHT-blocking therapy, low-level laser devices and targeted nutritional support through our Replenology range. These treatments work together to slow shedding, strengthen existing hair and improve scalp health. DHT-blocking therapies are discussed carefully to ensure safe and appropriate use.
Advanced Regenerative Medicine for Hair Loss
Leading Technologies Designed to Support Follicle Health
As one of the UK’s leading regenerative medicine clinics, we offer advanced biologically driven treatments using systems such as Magellan™, Angel Arthrex™, and our entry-level Neogenesis platform. These technologies produce high-purity cellular concentrates that support follicle strength and encourage healthier hair growth.
Exosmart™ – A UK First at Rejuvence Clinic
Rejuvence Clinic is the first clinic in the UK to offer Exosmart™, an autologous exosome system that isolates powerful regenerative vesicles from your own blood. Exosmart™ enhances follicle activity, promotes thicker growth and supports long-term hair stability using your body’s own biology.
Considering Surgical Hair Restoration
When Hair Transplant Surgery Should Be Considered
While some men may eventually benefit from a hair transplant, this is best viewed as a final step, not the first. Instead of performing surgery in-house, we refer patients to some of the most reputable transplant surgeons in the UK, ensuring the highest standards of surgical care.
Why a Combined Approach Works Best
At Rejuvence Clinic, the most successful outcomes come from personalised treatment plans that integrate proven medical therapy with advanced regenerative options. This combined approach helps achieve stronger, denser and more resilient hair.
©Individual results may vary.
What are Medical Hair Loss Treatments and How do We Enhance Them at Rejuvence Clinic?
For many years, male hair thinning has been managed with a small group of clinically proven medical therapies designed to slow shedding, strengthen existing hair and improve overall scalp health. These traditional treatments remain an important foundation in managing hereditary hair loss across the UK. At Rejuvence Clinic, we elevate these options by combining established medical approaches with advanced regenerative hair restoration, including cutting-edge cellular systems and innovative growth-factor-based therapies. This integrated strategy allows us to address the root causes of hair loss more effectively, delivering stronger, more natural and longer-lasting improvements for our patients.
A number of topical foams, lotions and oral tablets are now heavily advertised for male and female hair loss, but it is important to understand that these products are not new. The original active ingredient they rely on has been available for decades, and its patent has long expired—allowing multiple companies to release their own versions under different brand names.
These topical hair-regrowth solutions help support hair density by improving blood flow to the follicle, encouraging follicles to shift from the resting phase into active growth, and extending the duration of the growth cycle. They also help counteract the gradual thinning process known as miniaturisation, which is central to male pattern hair loss. Users typically begin seeing noticeable improvements in 9 to 12 months, provided the product is used consistently. However, stopping treatment often results in newly improved hairs gradually shedding, as the follicles return to their original cycle.
More recently, many clinics and online subscription companies have promoted oral hair-regrowth tablets as a more convenient alternative to topical application. These tablets work in a similar way but avoid the need for twice-daily scalp application, making them easier to incorporate into a routine. At Rejuvence Clinic, our medical team carefully assesses whether topical or oral therapy is more suitable based on individual health, goals and stage of hair loss, ensuring a safe and effective treatment plan tailored to each patient.
DHT blockers have also been used in the treatment of androgenic alopecia. This group of medication blocks the action of five alpha reductase and hence reduces the amount of dihydrotestosterone. As a result hair loss is reduced. There were initially fears that they may increase the risk of prostate cancer but these fears have been shown to be incorrect. Despite DHT blockers being more effective than minoxidil and caffeine in treating hair loss it can be associated with significant side effects. A proportion of men have complained of reduced sex drive and weaker erections, both of which seriously compromise their sex life. More recently, a weak association has been found between long term DHT blockers use and mental health problems such as depression and even psychosis. Despite all of this, this is the medication of choice for those ultimately considering a hair transplant.
Shampoos containing caffeine have been shown in recent studies to improve hair regrowth. Caffeine has been shown to block the effects of five alpha reductase and hence prevent the conversion of testosterone to dihydrotestosterone. This helps to reduce hair loss and assist hair regrowth. Caffeine’s ability to increase blood supply to the scalp is also beneficial for hair follicles.
Numerous practitioners have claimed spectacular results with injections of cocktails containing vitamins and plant extracts. Limited scientific evidence exists for their effectiveness. In fact what has been published in scientific journals sites nasty allergic reactions that have resulted in scarring and left patients with permanent hair loss. Be wary of spectacular claims from clinics offering mesotherapy for hair loss.
At Rejuvence we offer intravenous vitamin drips tailored to specific needs. Our Hair Boost Drip consists of a combination of vitamins and biotin and can help improve the quality of your existing hair as well as improve hair loss.
Microneedling combined with cellular regenerative treatment is rapidly becoming a highly effective option for male pattern hair loss. Studies in both men and women have shown improvements of 10–15% in hair thickness and density after just three sessions over three months. These treatments are well tolerated, minimally invasive and can be precisely targeted to thinning areas of the scalp while leaving stronger hairs untouched—making them an ideal choice for early and moderate stages of hair loss.
Many clinics in the UK offer growth-factor-based therapies for hair loss, but the quality and concentration of the biological serum varies widely. Research shows that optimal results are only achieved when the cellular concentrate reaches 4–5 times the natural baseline. Most clinics rely on simple test-tube systems which typically produce concentrations of only up to twice the baseline—often even lower—resulting in less effective treatment outcomes.
At Rejuvence Clinic, we use Magellan™ and Angel Arthrex™, two of the most advanced cellular systems available. These devices produce high-purity, optimally concentrated bio-regenerative serum that supports follicle activity and delivers noticeably better results. Angel Arthrex™ can also tailor the cellular profile to create a more anti-inflammatory formulation, which is particularly helpful for conditions such as alopecia areata.
If you are experiencing thinning, shedding or early hair loss, we invite you to book a consultation and discover how our advanced regenerative approach can help restore thicker, healthier hair.
Exosomes for hair loss - A new BREAK THROUGH treatment for hair loss!
Exosomes are a new break through treatment alternative for hair loss. Exosomes are produced by almost all cells in the body. They are essentially small packets released by cells containing a variety of proteins, growth factors, specific genetic material called RNA and mRNA as well as signalling molecules. These packets have a ‘lipid bilayer’ wall and are extremely small. This means they are easily absorbed by surrounding cells and able to easily deliver their contents. Cells of particular organs produce specific types of exosomes. Exosomes are capable of promoting tissue regeneration, new blood vessel development as well as having anti-inflammatory properties. When specific types of exosomes are delivered to the scalp they can initiate new hair growth.
Where do Exosomes come from?
Exosomes are generally obtained from three main sources. They can be derived from plants, animals or humans. Ideally, the science suggests that the most effective exosomes are likely to be derived from humans and specifically from stem cells in the umbilical cord or mesenchymal stem cells. These stem cells have the greatest ability to remodel into any other cell and hence likely to produce exosomes that are the most versatile. At present there are a number of groups in South Korea and the United States that have successfully mass produced human derived exosomes from mesenchymal stem cells and are trialing these in a multitude of medical conditions. However, all human derived products including exosomes are banned in the UK and Europe and hence not available. Plant derived exosomes and animal derived exosome products are available on the market and are approved for use in the UK. They have also been shown to be effective in a variety of conditions including hair loss.
Leading the UK in Autologous Exosome Hair Loss Treatment – ExoSMART™
At Rejuvence Clinic, we are proud to be the first clinic in the UK to introduce the ExoSMART™ autologous exosome system for hair loss, bringing a new level of innovation to regenerative hair restoration. ExoSMART™ isolates and concentrates powerful exosomes and biologically active growth factors directly from your own blood, including VEGF (vascular endothelial growth factor), PDGF (platelet-derived growth factor), TGF-β (transforming growth factor beta), EGF (epidermal growth factor) and other signalling molecules essential for follicle repair and regeneration. These concentrated messengers support healthier follicles, improve scalp condition and encourage stronger, denser hair growth. ExoSMART™ integrates seamlessly with our advanced cellular systems—Magellan™ and Angel Arthrex™—allowing us to create tailored, multi-layered regenerative protocols for men experiencing thinning, reduced density or early hair loss. As a leading centre for regenerative medicine in London, Rejuvence Clinic combines cutting-edge science with expert medical care to deliver exceptional, natural-looking results.
A hair transplant is not always the best solution!
Many suffering with hair loss believe that a hair transplant is the ultimate solution for their problem. Indeed aggressive advertising and cost cutting by clinics predominantly based in Turkey has meant that a hair transplant is potentially affordable for many more now. However, it is very important to understand that opting for a cheap hair transplant abroad by no means guarantees the best possible result. Indeed if a hair transplant goes wrong and the implantation pattern is substandard results can not be reversed. A hair transplant is the last resort. The most number of hairs that can be transplanted in one sitting is around 3000. These hairs are strategically implanted into a region that, in its prime, had between 30000 to 40000 hairs. Hair transplantation is no more than a treatment of last resort where there are no other options left.
In contrast early treatment with plasma therapy and new biocellular techniques on offer at Rejuvence can potentially mean you can save what hair you have and have hair regrowth much greater than any hair transplant can achieve. So before you jump to a hair transplant consider plasma therapy and biocellular hair treatments at Rejuvence Clinic.
REPLENOLOGY Hair Supplements - Replenishment & Nourishment
REPLENOLOGY Hair is a four part natural system formulated for use by both women and men to fully replenish nutrients that are lacking when experiencing hair loss and that are necessary for healthy hair. These nutrients target 21 causes of hair loss and support normal scalp & intrinsic hair functions along with providing cosmetic benefit to protect and improve the look of healthy and fuller hair. The Replenology Hair Daily Dietary Supplement can be combined with Replenology Daily Shampoo and Daily Conditioner. In addition the Daily Advanced Follicle Nutriment is a topical product that can be applied to specific patches of hair loss in much the same way as topical Minoxidil.
Replenology Hair works by replenishing nutrients in the hair follicles that have been depleted due to ageing, diet, hormonal changes, environmental effects, certain medication and long term exposure to chemical ingredients in some hair products.
What are the benefits of Replenology?
Replenology Hair has been formulated to target 21 known causes of hair loss and shown to replenish nutrients in the hair follicles that are not normally found in a regular diet and hair care products, including natural stilbenes, wedelolactones, procyanidins. Replenology Hair is not a drug with associated potential side effects.
When will I see results? Replenology Hair begins working for you on the 1st day of use and you may see results as early as 4 to 8 weeks after commencing daily use. However, it may take 4 to 6 months to notice an effect. This will depend on how depleted the nutrients are in each individual and other overall health factors. You may notice a reduction in hair fall within 4 to 8 weeks followed by fuller and healthier looking hair on the scalp within 4 to 6 months. Once you begin using the Replenology Hair four part system you may experience an improvement in your wellbeing and energy levels due to the multiple vitamins, minerals and botanicals, that are rich in nutrients, amino acids and antioxidants, found in each of the Replenology Hair products. An improvement in the overall condition of your scalp and hair may also be experienced due to the nourishment that Replenology Hair will provide for you. The gentle but powerful ingredients will also protect your hair against the effects of everyday pollution and ultraviolet exposure.
Does Replenology actually work?
Replenology is a novel botanical natural product treatment for male and female pattern hair loss. A recent multi-author study (systematic review and Bayesian network meta-analysis) comparing improvements in hair growth across the main non-surgical hair loss treatments for male and female pattern hair loss including minoxidil, Low Level Laser Therapy (LLLT), DHT blockers and Viviscal™. Replenology supplements demonstrated a statistically significant increase in terminal hair density in men and women that was greater than that observed for other treatment modalities included in the study. Women were found to have an accelerating terminal hair regrowth rate between 3 months and 6 months. Men had a continuous regrowth rate. Replenology did not demonstrate any signs of resistance whereas resistance was evident in all other treatment regimens. The study concluded that a multi-targeting treatment approach is required and that Replenology combined with other treatments such as plasma therapy show potential promise. However, statistical evidence of a superior response with Replenology compared to other more established non-surgical hair loss treatments does not mean it should completely replace minoxidil, and/or DHT blockers.
At Rejuvence Clinic we stock Replenology products and specifically sell the Professional Grade Supplement. For further details on the Replenology product line and whether it could benefit you in your battle against hair loss call us on 0207 531 6600 or WhatsApp us.
SkinTide for Hair Rejuvenation at Rejuvence Clinic
At Rejuvence Clinic, SkinTide is offered as an advanced regenerative option for improving scalp health and supporting hair rejuvenation. This scientifically engineered peptide complex can be used alone or combined with our cellular regenerative systems to enhance results. SkinTide delivers bioactive ingredients designed to improve follicle environment, strengthen existing hairs, and create a healthier foundation for long-term hair density.
How is SkinTide Used for Hair Loss at Rejuvence Clinic?
SkinTide is applied to the scalp after microneedling or targeted delivery, allowing the active compounds to penetrate more effectively into the superficial dermal layer. Treatments are directed precisely at thinning or weaker zones, making it suitable for early and moderate stages of male or female hair thinning. Because SkinTide is gentle, non-invasive and well tolerated, it is a strong option for patients seeking a biologically driven boost without discomfort or downtime.
How does SkinTide Work? – Peptides and Scalp Regeneration
SkinTide contains a specialised blend of bioactive peptides, copper complexes and regenerative signalling molecules designed to improve the health of the scalp and support stronger hair growth. These actives work to:
Improve microcirculation around the follicles
Support a healthier growth environment
Extend the active (anagen) phase of the hair cycle
Strengthen existing hair fibres
Reduce inflammation and oxidative stress in the scalp
By enhancing the scalp’s biological environment and promoting healthier cellular activity, SkinTide helps create better conditions for improved thickness and resilience over time.
Can Microneedling With Sylfirm X stimulate hair growth?
At Rejuvence Clinic, Sylfirm X radiofrequency microneedling plays a central role in our advanced hair restoration protocols. Unlike older devices such as Morpheus8 or Potenza, Sylfirm X uses ultra-precise pulsed RF technology that delivers controlled energy with significantly less trauma. This allows us to safely target the deeper layers of the scalp, enhancing microcirculation, reducing inflammation and improving the environment needed for follicles to transition into the active growth phase. Its precision and tolerability make it one of the most effective RF microneedling systems available for male and female hair thinning.
Combining Sylfirm X With Diamond Exosome, SkinTide & Target Cool
To maximise results, Sylfirm X is often paired with Diamond Exosome, SkinTide peptide complexes or needle-free mesotherapy using Target Cool. These regenerative serums are delivered directly after RF channels are created, or via painless, pressure-assisted infusion, allowing for deeper penetration and stronger biological signalling. Together, this combination boosts scalp health, supports follicle repair and helps promote visibly thicker, healthier hair. As a leading centre for regenerative hair treatments in London, Rejuvence Clinic offers a comprehensive, medically led approach that blends RF technology, regenerative serums and precision delivery for exceptional non-surgical hair rejuvenation.
Rejuvence Philosophy
At Rejuvence Clinic, we treat male pattern hair loss through a combined medical and regenerative approach that strengthens follicles and supports long-term scalp health. By integrating microneedling, advanced cellular regenerative treatments and targeted Replenology supplementation, we create an optimal environment for improved hair density and resilience.
Early regenerative therapy can help slow progression and prepare the scalp for any future surgical options. For those seeking the next level of treatment, our biocellular techniques, including nanofat-based regenerative solutions, offer enhanced support for healthier, stronger hair.
Through our ability to blend medical therapy, regenerative science and energy-based devices, Rejuvence Clinic delivers a comprehensive, results-driven strategy for managing male pattern hair loss. Book a consultation to discover the best tailored plan for you.
