O-Shot® Treatment London, UK

O-Shot Treatment London

Sexual function is an extremely important aspect of life for women of all ages. Sexual function is closely related to overall well-being as well as relationship satisfaction. As women get older most still consider sex just as important. However, 45% of midlife women have sexual problems, and almost 15% have a sexual problem that causes significant physical and/or mental stress. The O-ShotⓇ at Rejuvence Clinic is part of our sexual rejuvenation treatment package for improved sexual function in women. 

Sexual function & Orgasm

Orgasm is defined as the culmination of sexual arousal. Around 90% of women report orgasm from some form of sexual stimulation. Most women do not regularly orgasm from sexual intercourse alone. In contrast almost 100% of men experience orgasm solely from sexual intercourse. 


The difficulty of achieving orgasm for women is very real with at least 10% of women having never had an orgasm. For women, orgasm can be achieved from direct or indirect clitoral stimulation, vaginal stimulation or stimulation of areas around the vagina. Clitoral stimulation is regarded as the most important trigger for orgasm.

O-Shot Treatment London 1

Sexual Dysfunction

Female sexual dysfunction is a broad term that includes painful sex (also known as dysparaeunia), difficulty in achieving orgasm, vaginal dryness, reduced sexual arousal and low sexual desire. All of these are considered sexual dysfunction especially when they are associated with distress. 


Causes of sexual dysfunction can be physical and/or mental in nature. Sexual function tends to decline with age, often due to menopause. Hormonal changes can result in shrinking of the vagina and vulva resulting in vaginal bleeding, vaginal burning, irritation, and pain and discomfort with sex. Urinary incontinence, weakening of pelvic muscles, prolapse and vaginal dryness can significantly affect sexual satisfaction. Multiple medical problems, including diabetes, high blood pressure and endometriosis also impact on sexual function.

Physical Causes

Psychosexual causes of sexual dysfunction

Everyday life stressors also have a negative impact on sexual function in women. Job-related stress and financial concerns, difficult relationships, caring for children and aging parents as well as past sexual trauma all contribute to sexual dysfunction. Depression and anxiety are associated with poor sexual satisfaction and medication taken for such conditions only worsen the problem.

Psychosexual Causes

How can I improve my sex life?

Female sexual dysfunction is a complex condition and needs to be unpicked with the causes identified and separated into physical and psychological. For many women physical causes of sexual dysfunction stem from a reduced ability to be aroused due to impaired sensation of the clitoris and vagina. Sexual stimulation of women is known to be provided mostly by touching and the most sensitive part in the female body is the genital area. 

What is the O-Shot®?

The O-Shot® is a non-invasive treatment used to help improve your sexual function. This is achieved by directly treating the clitoris and vaginal walls. The O-Shot® can result in increased arousal from clitoral stimulation, increased natural lubrication, a tighter vaginal opening, stronger and more frequent orgasms, decreased pain for those suffering with dyspareunia, improved urinary incontinence and a smoother rejuvenated looking vulva. 

How does the O-Shot® work?

The O-Shot® was first described by Charles Runnels. It involves treating the clitoris and vaginal walls as well as the vulva with platelet rich plasma (PRP). Platelets are components of blood that help with healing wounds. When separated from blood and concentrated – platelet rich plasma – they can result in the release of large amounts of growth factors and stem cells. Areas treated with PRP get flooded with growth factors and stem cells and this results in the formation of collagen, nerve regeneration and new blood vessels. In the case of the clitoris and vagina, there is improved sensation, thicker vaginal walls and better functioning cells. 

What is the ‘G-Spot’?

The G-Spot, also known as the Grafenberg spot, has been described as an elusive point of pleasure for all women seeking sexual nirvana. Many areas have been described as being the G-spot but does it actually exist. A review of 60 years worth of research has concluded that it probably doesn’t exist. However, rather than a spot, it is more appropriate to refer to the G-spot as an area of the greatest density of nerves that, when stimulated, can help a woman achieve orgasm during sex. 

Studies have found that the distal anterior vaginal wall (the upper wall of the vagina close to the opening) has the greatest density of nerves compared to other areas of the vagina alongside the clitoris. Sexual stimulation of these areas through touching and penetrative sex is most likely to result in a woman having an orgasm.

Does the O-Shot® treat the G-spot?

The O-Shot® specifically targets the clitoris and the distal anterior vaginal wall. PRP injected into these areas helps with the proliferation of new collagen, nerves and blood vessels. This results in improved sensation and tightening in these areas and hence makes it more likely for a woman to reach orgasm. 

What about the clitoris?

It is rare for women to achieve orgasm simply through direct stimulation of the so-called G-Spot. This is why penetrative sex alone is often NOT enough to climax. Most women require sexual stimulation of other erogenous zones. The most sensitive of these erogenous zones is the clitoris. The most visible part of the clitoris is referred to as the glans clitoris and is the size of a pea. It is located just above the urethra (opening for passing urine). The glans clitoris has the greatest density of nerve endings and is extremely sensitive to touch. 

Most of the clitoris is actually not visible. Connected to the glans is the body of the clitoris that splits into two and forms two ‘legs’, known as the crura and vestibular bulbs. The bulbs or ‘legs’ extend behind and around the vagina. Unlike the glans clitoris, the crura and vestibular bulbs contain erectile tissue similar to the male penis and swell up with blood during sexual stimulation. They help increase lubrication in the vagina and the swelling increases sensation during sex, especially in the G-Spot area. 

What can the O-Shot® do for the clitoris?

The O-Shot® involves treating the clitoris with PRP. PRP injected into and around the clitoris, as with the G-Spot, results in increased growth factors and stem cells helping to generate new collagen, nerves and blood vessels. These work together to rejuvenate the skin, increase sensation in the glans clitoris and improve blood flow and swelling of the vestibular bulbs. The result is more pleasurable sex and better orgasms!

Dr Mamuza is our Associate Specialist for Cosmetic Gynaecology and Intravenous Vitamin Drips. She has pursued an interest in non-invasive procedures in aesthetic gynaecology and urology through the Cellular Medicine Association, specialising in the O-Shot® and P-Shot® procedures. Believing strongly in an integrative approach to enhancement of feminine sexuality, Dr Mamuza has developed her skills through multiple international courses and workshops.

How is the O-Shot® performed?

At Rejuvence we are licenced to provide our clients with the O-Shot®. Our resident specialist in aesthetic gynaecology, Dr Jasna Mamuza, is able to offer this treatment in clinic. The O-Shot® is a non-invasive treatment that takes around 1 hour to perform.


● Topical anaesthetic (numbing) cream is applied to the clitoris, vulva and vaginal opening.

● Blood is taken and highly concentrated platelet rich plasma (PRP) is prepared using the Angel Arthrex system. 

● Once ready the PRP is then injected into and around the clitoris.

● PRP is also injected into the vulva to improve and rejuvenate its appearance. 

● Finally PRP is injected into the distal anterior vaginal wall – the ‘G-Spot’.

The O-Shot® involves treating the clitoris with PRP. PRP injected into and around the clitoris, as with the G-Spot, results in increased growth factors and stem cells helping to generate new collagen, nerves and blood vessels. These work together to rejuvenate the skin, increase sensation in the glans clitoris and improve blood flow and swelling of the vestibular bulbs. The result is more pleasureable sex and better orgasms!

The O-Shot® has other additional benefits. Studies have been published demonstrating significant improvements in vulval and vaginal lichen planus when treated with PRP. Lichen planus of the vulva and vagina includes soreness, burning and raw skin around the vulva with white streaks and a red, pink or pale white colour. This can adversely affect sexual stimulation of the vulva and clitoris. When the vagina is also affected, similar changes occur on the walls and can make sexual intercourse very painful. The O-Shot® can significantly improve these symptoms. 

During childbirth, many women suffer from tears to the vaginal wall and end up with episiotomy scars. These scars can be painful and unsightly. They can make sex very uncomfortable and negatively affect body image. The O-Shot® can help to improve the scars and reduce associated pain. 

There is very minimal discomfort associated with this treatment. Thanks to the numbing cream applied beforehand there is practically no pain upon injection of the PRP into and around the clitoris, as well as the vulva and vaginal walls. 

The O-Shot® is associated with minimal bruising and practically no complications. 

There is no downtime associated with this treatment. You can quickly get back to all your regular activities such as work, exercise and even having sex on the same day. 

The majority of women notice improvements in their sex life within 3 to 4 weeks. However, some report positive gains quicker than this. Sensation in the clitoris and vagina is improved with more noticeable orgasms that are also more frequent. It can also help with better natural lubrication, reduced pain during sex as well as improvements to the surrounding skin, urinary incontinence and general sexual arousal. 

The majority of women get improved orgasms and sexual satisfaction from a single treatment. However, studies have shown that the effects of the O-Shot® are improved with repeated treatments and this is especially the case with women suffering from significant sexual dysfunction. The treatment can be repeated a further 2 times with sessions taking place at 4-6 week intervals. Often a maintenance treatment is recommended every 9 to 12 months. 

As with any treatment, the O-Shot® does not work for everyone all the time. For those looking to improve on an already positive sex life, the O-Shot® works well. For those suffering with more complex sexual dysfunction, a series of sessions may be required although most women see significant improvements after the first treatment. Psychosexual counselling is also recommended. 

Psychosexual counselling at Rejuvence

At Rejuvence we are striving to provide all our clients with the best possible care at an affordable price. Unlike many other clinics we advocate strongly combing psychosexual counselling with all our O-ShotⓇ treatments. Prior to your treatment, our resident Psychosexual expert, Dr Venkat Sivaraj, carries out a psychosexual evaluation to help clients try to understand their needs and any sexual dysfunction. This is to help evaluate whether the O-ShotⓇ is appropriate for a client. The service is included for free with the O-ShotⓇ and Dr Sivaraj is always available to help clients following their treatment. At Rejuvence we believe the psyche is just as important for a fulfilling sex life as the physical ability to orgasm. 


Book a consultation with us. Call us on 0207 531 6600. 


We are in the midst of a pandemic and it is essential that we maintain the safety of our patients as staff above all else. Before attending Rejuvence Clinic for your appointment please review the following safety guidelines. 


If you have tested positive for COVID-19 or have symptoms, or if you live with someone with COVID-19 or someone with symptoms, please notify us immediately.


If you or someone you live with has any symptoms such as fever, dry cough, sore throat, fever, chills, shaking, muscle pain, headache, new loss of taste or smell, you MUST NOT attend. Please call us immediately and we will reschedule your appointment.


Once you arrive at clinic, please press the intercom. Upon answering you will be asked to come into the building and wait in the lobby. You will be met by one of our staff. 

Everyone must have a wellness check prior to coming in:

  • You must wear a face mask at all times
  • We will check your temperature with a no-touch wall mounted thermometer. If you have a high temperature you will be asked to leave and we will reschedule your appointment. 
  • Please do not bring anyone else with you to your appointment. This is to minimise risk to both staff and patients.
  • Please sanitise your hands using the wall mounted alcohol no-touch sanitiser. 
  • Please wear shoe covers before entering. 


Only patients with scheduled appointments will be allowed into the clinic.  You must come alone – no guests, family, or and friends can come with you into our clinic at this time.

No walk-ins are allowed, only scheduled appointments. Please call us on 0207 531 6600 or Whatsapp us on 07504 552772 with any questions or to purchase products.


All staff, and anyone entering our clinic will be wearing masks. Depending on your treatment, clinicians may also wear goggles and face shields. Our staff will have daily wellness checks including temperature readings and symptom monitoring.

We appreciate you abiding by our safety guidelines to keep our staff, other patients, and our community healthy.


Vulnerable people at high risk of severe illness from COVID-19 should only leave home for medical care and essential activities. Virtual consultations are available with Rejuvence Clinic. Please contact us directly at 0207 531 6600 or Whatsapp on 07504 552772 to schedule your virtual consultation.


We appreciate you abiding by our safety guidelines to keep our staff, other patients, and our community healthy.

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