Anti Ageing


Ageing of the human face is a complex process and is not limited to just the skin. It is a three-dimensional process affecting skin, fat, muscle and bone. Research into this field of medicine is now starting to mature and we are able to predict and understand, in a simplified manner, how we age.


How does the skin age?

Skin health and the maintenance of skin health involves numerous strategic cells and processes. Our skin is at its best while we are still children. Up to the age of 10 years skin can be defined as being smooth, even in colour, firm, tight, well moisturised, tolerant and the process of skin cell repair and regeneration is regular. There is no sebum (oil) production, no inflammation, no dryness and no sensitivity. During our teenage years skin health begins to deteriorate and function becomes altered. Our skin starts to produce sebum, becomes inflamed, and as a result we start to develop irregular textures and enlarged pores, acne, uneven skin colour, and a dull appearance.


By the age of 30, skin becomes inactive. The turnover of skin cells becomes extremely irregular. The skin’s barrier function becomes weak. A lack of cellular activity means critical structures within the skin become depleted, abnormal in structure and hence skin starts to develop lines and wrinkles. There are three main components of the skin that are the focus of the majority of anti ageing treatments. These are collagen, elastin and hyaluronic acid. Treatments that are aimed at increasing their levels as well as optimising the conditions for their production, repair, and regeneration produce the best anti ageing effects.

What happens to fat with ageing of the face?

As mentioned earlier facial ageing is a three-dimensional process. Below the skin of the face is a complex arrangement of self contained parcels of fat. These parcels of fat are arranged either side of the SMAS (muscular system of the face). The deep parcels of fat provide the mid-face with volume and youth. As we age the deep parcels of fat reduce and essentially deflate. This results in loss of volume of the mid-face. The superficial parcels of fat are more variable in their behaviour.


In some people the superficial fat parcels can increase in size and alongside weakened ligaments result in sagging of the mid-face and jawline producing tear troughs, nasolabial folds and jowls. In others the superficial fat parcels deflate with age, there is overall loss of volume in the face. The face can then take on a skeletonised facial appearance. A thorough understanding of the location of different parcels of fat and how they are behaving can lead to excellent results when using dermal fillers and fat transfer to restore balance and plump to the face.

J-Plasma Face – Press the RESET button!

At Rejuvence we are the first and only clinic to bring this revolutionary treatment to the UK. It has taken the US by storm. Prominent US cosmetic doctors regard J Plasma as the greatest innovation in the cosmetic industry in the last 10 years. J Plasma Face helps to hit the reset button and can take 5 to 10 years off someone. J Plasma Face is similar to Fraxel CO2 laser but better. It has the effect of a non-invasive facelift and the results can be stunning. For further details please contact us to book a consultation.


Chemical Peels:

Obagi Blue Peel Radiance 
ZO Three Step Peel 


Dermal Fillers 

From £240.0

Platelet Rich Plasma
(includes microneedling)


Stem Cell Rejuvenation

From £1500.00


From £750.00

Wrinkle Relaxation Injections

From £220.00

ZO Medical Retinol Skin Brightener (1.0%)  


ZO Phase I Daily Skin Care Program


ZO Phase II Anti-aging Program


ZO Phase III Aggressive Anti-aging Program


Rejuvence Philosophy

At Rejuvence we have a thorough understanding of the processes involved in the ageing of the face. We are keen to emphasise the 3 dimensional nature of the ageing process and hence ageing at multiple levels need to be addressed in order to achieve good results. In addition we are passionate about using evidence based treatments. Over recent years doctors have realised that treatments, however simple or complex, are about discussing options and shared decision making with their patients. As doctors we have a responsibility to our patients to provide them with treatment options that have the best levels of evidence to prove their efficacy. In the cosmetic industry this, unfortunately, is not always the case. At Rejuvence we are passionate about offering our clients evidence based treatments that have been shown to work. Where the evidence base is not very strong we are quick to point this out. We are the experts in anti-ageing and aesthetic medicine but we also acknowledge you are the experts of your face.


Collagen provides the skin with its tensile strength and is dependent upon a criss-cross structure in the dermis (deep layer) of the skin. As we age the amount of collagen reduces and it loses this arrangement. As a result skin is thinner and loses its strength. Excessive sun exposure, smoking and high caffeine consumption can worsen this process.

Elastin forms a unique relationship with collagen and provides the skin with its elastic properties. With age the amount of elastin reduces and its interaction with collagen is compromised. Skin becomes lax and loose. It tends to sag. Excessive sun exposure and smoking can worsen this process significantly.

Hyaluronic acid is found in large quantities in healthy skin. It is responsible for carrying large numbers of water molecules and provide skin with hydration and gives it a plump and soft feel. With ageing levels of hyaluronic acid reduce and skin can dry out and become sallow and dull. As is the case with collagen and elastin, the process of ageing and reduction of hyaluronic acid is significantly worsened by excessive sun exposure and smoking.

Treatment specifically targeted at the skin includes topical skincare products including serums and creams that help to increase fibroblast activity. Fibroblasts are responsible for collagen and elastin production. Retinol and tretinoin are the best studied products and have been shown to increase collagen and elastin levels. Chemical peels can be used to improve skin texture following adequate skin preparation. Specific collagen induction therapies including micro needling result in increased collagen levels. Platelet rich plasma with micro needling can have a dramatic effect on increasing fibroblast activity and can return a glow to aged skin. This can last up to 18 months. Ultimately the effects of these treatments will be short lived if specific lifestyle changes are not made including reduced sun exposure and smoking cessation. Healthy skin function can be maintained irrespective of age as long as a good skincare program is used.

Regions of volume loss can be addressed using dermal fillers. Injections of hyaluronic acid into the deep fat compartment can go a long way to restoring a youthful appearance. The ultimate natural filler is, of course, your own fat and fat transfer provides the best long term solution to volume loss.

Where there is excessive volume in the superficial fat parcels and together with weakening of ligaments, there is a general sagging of the face. Gravity also plays a significant role over time. In this case a lifting effect is required. This can be achieved with appropriate placement of dermal fillers or fat, to emphasise cheek regions. Sagging jawline can be hidden with clever placement of hyaluronic acid dermal fillers. A direct lifting effect can be provided by the use of threads such as PDO or PCL threads that can be used to lift the jawline and cheek as well as tighten the neck.

With ageing there are changes to the muscles of the face. Most notably with the increased use of facial muscles with age they hypertrophy (increase in size and become stronger). As a result they can over stretch the skin and deeper structures. Alongside increased laxity and thinning of the skin with age, there are increases in wrinkling especially around the forehead and the corner of the eyes (crow’s feet). The down turn of lip corners (marionette lines) and cords in the neck can also form as a result of muscle hypertrophy (increase in size and strength).

The use of wrinkle relaxing injections is amongst the oldest aesthetic techniques. Injection of botulinum toxin type A into regions of the forehead and corners of the eyes as well as around the bridge of the nose can help in the reduction of dynamic facial lines. Dynamic lines are lines that are only seen on moving certain parts of the face in frowning, smiling and in raising the eyebrows. Static lines describe wrinkles and fine lines that are always present irrespective of facial movements. These are only partially treated with wrinkle relaxing injections.

Despite the great advances in fillers and threads the effects of treatment are short lived. Fillers tend to last around 9 to 12 months before they need topping up. Threads can last upto 2 years depending on whether PDO or PCL threads are used. Your own fat is considered the ultimate ‘natural’ filler. Using minimally invasive VASER liposuction techniques fat can be harvested from the tummy of flanks and then injected back in the face to act as a natural filler. The results of fat transfer to the face last much longer, depending upon lifestyle choices. With fat transfer there is also the added bonus of stem cells. Fat cells have been found to be an excellent source of stem cells. Stem cells can be considered ‘baby’ cells that have the ability to turn into any other cell in the body. By using innovative micronising techniques, fat cells can be broken up to release stem cells and growth factors. When these are injected under the skin, they have a phenomenal rejuvenating effect and provide results even better than PRP. For further details please contact us to book a consultation.


We are in the midst of a pandemic and it is essential that we maintain the safety of our patients as staff above all else. Before attending Rejuvence Clinic for your appointment please review the following safety guidelines. 


If you have tested positive for COVID-19 or have symptoms, or if you live with someone with COVID-19 or someone with symptoms, please notify us immediately.


If you or someone you live with has any symptoms such as fever, dry cough, sore throat, fever, chills, shaking, muscle pain, headache, new loss of taste or smell, you MUST NOT attend. Please call us immediately and we will reschedule your appointment.


Once you arrive at clinic, please press the intercom. Upon answering you will be asked to come into the building and wait in the lobby. You will be met by one of our staff. 

Everyone must have a wellness check prior to coming in:

  • You must wear a face mask at all times
  • We will check your temperature with a no-touch wall mounted thermometer. If you have a high temperature you will be asked to leave and we will reschedule your appointment. 
  • Please do not bring anyone else with you to your appointment. This is to minimise risk to both staff and patients.
  • Please sanitise your hands using the wall mounted alcohol no-touch sanitiser. 
  • Please wear shoe covers before entering. 


Only patients with scheduled appointments will be allowed into the clinic.  You must come alone – no guests, family, or and friends can come with you into our clinic at this time.

No walk-ins are allowed, only scheduled appointments. Please call us on 0207 531 6600 or Whatsapp us on 07504 552772 with any questions or to purchase products.


All staff, and anyone entering our clinic will be wearing masks. Depending on your treatment, clinicians may also wear goggles and face shields. Our staff will have daily wellness checks including temperature readings and symptom monitoring.

We appreciate you abiding by our safety guidelines to keep our staff, other patients, and our community healthy.


Vulnerable people at high risk of severe illness from COVID-19 should only leave home for medical care and essential activities. Virtual consultations are available with Rejuvence Clinic. Please contact us directly at 0207 531 6600 or Whatsapp on 07504 552772 to schedule your virtual consultation.


We appreciate you abiding by our safety guidelines to keep our staff, other patients, and our community healthy.

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