At Rejuvence Clinic, we are proud to be the first clinic in the UK to introduce Exosmart™ Autologous Exosomes—a revolutionary regenerative treatment offering new hope for patients suffering from alopecia areata. Building on our reputation for advanced regenerative therapies, Exosmart represents a significant step forward in the natural, non-surgical treatment of autoimmune hair loss.
What Is Alopecia Areata?
Alopecia areata is an autoimmune condition where the body’s immune system mistakenly attacks hair follicles, leading to patchy hair loss on the scalp and sometimes on other areas of the body. It affects both men and women and can be emotionally distressing, especially when it progresses or fails to respond to standard therapies.
At Rejuvence Clinic, we’ve successfully treated many cases of alopecia areata using Platelet-Rich Plasma (PRP) therapy, particularly when combined with intralesional corticosteroid injections. Our use of the Angel Arthrex Level III PRP system allows us to extract a highly concentrated PRP solution, rich in regenerative growth factors that support follicle recovery. Many patients have experienced significant improvement in hair density and reduced shedding, particularly in early and moderate cases.
Introducing Exosmart™: Advanced Autologous Exosome Therapy
While PRP has proven effective, Exosmart™ takes regenerative therapy to the next level. Using a CE-MDR certified ultrafiltration system, Exosmart isolates and concentrates exosomes—tiny vesicles naturally secreted by platelets that carry powerful anti-inflammatory and growth-promoting signals.
Unlike stem cell therapies (which often require surgical harvesting or raise regulatory concerns), Exosmart uses only your own blood. Through a quick, in-clinic process, it delivers a high concentration of platelet-derived exosomes and regenerative proteins in just one session.
These exosomes are rich in:
- TGF-β and IL-10, which modulate immune response and reduce inflammation
- VEGF and PDGF, which promote angiogenesis and nourish hair follicles
- MicroRNAs, which support hair follicle regeneration and immune balance
Why Exosmart™ Has Huge Potential in Alopecia Areata
One of the key challenges in treating alopecia areata is immune system dysregulation. The inflammatory environment around affected hair follicles must be suppressed to allow regrowth.
Exosmart™ offers a unique anti-inflammatory mechanism of action. By delivering concentrated exosomes with immune-calming proteins, it may help:
- Reduce perifollicular inflammation
- Restore immune tolerance to hair follicles
- Reactivate dormant follicles for regrowth
Early research on exosomes in alopecia areata (particularly those from mesenchymal stem cells) has shown promising results in modulating immune responses and encouraging hair regrowth. While Exosmart uses autologous platelet-derived exosomes, the immune-balancing properties are shared and supported by emerging data.
Exosmart™ vs PRP: What’s the Difference?
While both PRP and Exosmart are autologous, natural treatments, Exosmart offers several distinct advantages:
- Higher concentration of regenerative signals, including purified exosomes
- Stronger anti-inflammatory effect, ideal for autoimmune conditions like alopecia areata
- Longer-lasting effects, potentially requiring fewer sessions than PRP
- Sterile, closed-system processing, ensuring purity and consistency
That said, PRP remains a highly effective option, especially when combined with intralesional steroid injections, and has been the cornerstone of our alopecia areata treatment protocols at Rejuvence Clinic for several years.
A Comprehensive Approach to Alopecia Areata
At Rejuvence Clinic, we understand that no single treatment fits all. That’s why we offer tailored treatment plans, combining:
- Exosmart™ autologous exosome therapy
- Level III Angel Arthrex PRP
- Intralesional steroid injections
- Microneedling and adjunctive therapies
This integrated approach allows us to address both the inflammatory and regenerative aspects of alopecia areata, improving the likelihood of visible, lasting results.
Final Thoughts
Exosmart™ represents a new frontier in the non-surgical, natural treatment of alopecia areata. With its powerful anti-inflammatory and regenerative properties, it offers a novel pathway to hair recovery—particularly for patients who may not have responded to traditional therapies.
As the first clinic in the UK to bring this cutting-edge technology to patients, Rejuvence Clinic continues to lead in regenerative hair loss treatments, providing science-driven, personalised care in a clinical environment you can trust.