A Clinical Insight from Rejuvence Clinic

 

In recent months, many aesthetic and dermatology clinics have started promoting a

“two-step treatment” for keloid scars, combining Plexr® plasma soft surgery with ablative CO₂ laser resurfacing.

These clinics often describe the approach as revolutionary, claiming excellent cosmetic results and superior outcomes.

At Rejuvence Clinic, we welcome innovation — but only when it is supported by strong clinical evidence. As a CQC-registered clinic led by GMC-regulated doctors, our priority is patient safety, long-term outcomes, and honest medical guidance.

This article explains what the Plexr + CO₂ approach really offers, where it may help, and why it is not a universal solution for keloid scars.

What Is the Plexr® + CO₂ Laser “Two-Step” Treatment?

 

The treatment is delivered in two stages:

Step 1: Plexr® Plasma Soft Surgery

• Uses ionised gas (plasma energy)
• Creates tiny, controlled micro-injuries on the skin surface
• Aims to stimulate healing and superficial skin contraction

Step 2: Fractional CO₂ Laser

• Penetrates deeper into the skin (dermis)
• Remodels collagen
• Improves texture and pigmentation

The Claim

When used together, these treatments are said to:

• Flatten keloid scars
• Improve colour and texture
• Deliver better cosmetic results than traditional treatments

But does the science support these claims for true keloid scars?

 

What Does the Medical Evidence Actually Show?

Some studies suggest limited benefits — but only in very specific cases.

 

What Research Supports

• Abdallah et (2021): Improvement in texture and pigmentation in mild hypertrophic scars
• Vescio et (2022): Better patient satisfaction in post-surgical scars
• Kim et (2023): Reduced recurrence only when combined with steroid injections and only in small keloids

Who May Benefit

🟢 This approach may be suitable for:

• Fitzpatrick skin types I–III
• Early-stage, flat keloids
• Facial or neck scars, where precision is essential

Key Limitations

🔴 Important limitations must be clearly stated:

❌ Not effective for large, mature, or recurrent keloids

❌ Higher risk of pigmentation changes in darker skin tones (Fitzpatrick IV–VI)

❌ No strong long-term randomised trials comparing it to gold-standard keloid treatments

❌ Risk of post-inflammatory hyperpigmentation (PIH) and scar reactivation

👉 This is not a standalone or curative keloid treatment.

How Rejuvence Clinic Treats Keloid Scars Differently

At Rejuvence Clinic, we treat keloids as a medical condition, not a cosmetic flaw.

There is no single treatment that works for every keloid. That is why we use a personalised, multi-modal approach based on scar biology, skin type, and recurrence risk.

 

Our Core, Evidence-Based Keloid Treatments

Gold-Standard Interventions

• Steroid injections (Triamcinolone)
• 5-Fluorouracil (5-FU)
• Cryoshape® Cryotherapy
• Surgical excision (when appropriate)
• Nd:YAG & Er:YAG lasers (Aerolase®)
• Sciton BBL – excellent for redness and pigmentation
• Sylfirm X RF Microneedling – deep remodelling, safe for all skin tones

 

These treatments are clinically proven to:

• Reduce scar thickness
• Control inflammation
• Minimise recurrence
• Improve colour and texture

Advanced Regenerative Treatments at Rejuvence

We also offer next-generation therapies that are not widely available in the UK:

• PRP (Platelet-Rich Plasma) – supports healing and reduces recurrence
• Autologous Exosomes (ExoSmart™) – accelerates tissue repair and controls inflammation
• Polynucleotides – improve cellular communication and tissue regeneration

These treatments are particularly useful for:

• Resistant or recurrent keloids
• Patients with darker skin tones
• Scars with high relapse risk

So, Where Does Plexr® + CO₂ Fit In?

At Rejuvence Clinic, we do not consider Plexr + CO₂ a core keloid treatment.

Instead, it may be used selectively as a cosmetic refinement step in very limited cases:

✔ Lighter skin tones

✔ Small, early, non-bulky keloids

✔ Facial scars where downtime must be minimal

For most patients — especially those with darker skin or recurrent keloids — safer and more effective alternatives exist, such as Aerolase® and Sylfirm X.

 

Why Rejuvence Consultations Are Doctor-Led and Paid

Keloid scars affect:

• Physical comfort
• Appearance
• Confidence
• Mental wellbeing

 

That is why our consultations are:

✔ Comprehensive – based on hundreds of treated cases

✔ Doctor-led – no sales consultations

✔ Evidence-driven – guided by real outcomes, not trends

Looking Ahead

We are also developing an AI-based clinical assistant, trained on:

• Real Rejuvence patient data
• Treatment outcomes
• Scar biology and recurrence patterns

This ensures every patient benefits from accumulated clinical intelligence, not guesswork.

Why Patients Choose Rejuvence Clinic

 

1.  Advanced Technology

From Cryoshape® to Sylfirm X, we treat all keloid types and skin tones.

2.  Complete Scar Management

We address:

• Thickness
• Pigment
• Redness
• Texture
• Recurrence risk
• Emotional impact

3. Clinical Integrity We do not follow trends. We evaluate them Rejuvence Clinic is:
   • CQC registered

• GMC guided
• Aligned with Good Medical Practice

If we offer a treatment, it is because it works — not because it is fashionable.

 

Final Verdict

The Plexr® + CO₂ “two-step” approach may help a very small group of patients, but it is not revolutionary in the treatment of true keloid scars.

 

Take the Next Step

👉 Book a Doctor-Led Consultation

🔬 Explore Our Advanced Keloid Scar Treatments Don’t follow cosmetic trends. Choose clinical truth.